Lymphocyte, large

 

Normal case - Lymphocyte, large

 

Normal case - Lymphocyte, large granular

 

Normal case - Lymphocyte, large granular

 

CHARACTERISTIC of Lymphocyte, large

Size

12 - 16 um in diameter

Cytoplasm

More abundant cytoplasm than small lymphocyte

Cytoplasm is weakly basophilic and stains pale blue

Have a dozen or so quite prominent azurophilic granules which contain lysosomal enzymes. These are called large granular lymphocytes, which are lymphokine-activated T cells and natural killer cells.

Nucleus

Round or slightly indented

Chromatin

Less condensed

Outline

Irregular

 

Reference:

  1. Blood Cells A Practical Guide, Barbara J. Bain, 2nd Edition,1995. P.87

Last updated on 25 February, 2000.

Prepared by HKMTAQAP Haematology & Serology Panel.

Copyright 2000 HKMTAQAP. All Rights Reserved.